Biogenic Amines

Stimulation of 5-HT1A receptor with 8-OH-DPAT decreased frequency of GABAergic synaptic event in control rats without early postnatal FS (Non-FS), whereas 8-OH-DPAT did not change the frequency in 2w-FS group. 8-OH-DPAT did not change the amplitude of GABAergic synaptic events neither in Non-FS nor 2w-FS group. It was indicated that aversive stress exposure during the early postnatal period decreases 5-HT1A receptor-mediated inhibition of GABAergic mechanisms in adult rat mPFC. Early postnatal 2w-FS attenuated 5-HT1A control of GABAergic regulation which may contribute to abnormal behavioral response in adult rats.

Shinichi Kimura et al. BIA 25(4), 2011


Vol. 25 - Nr. 4 - 2014


Attenuation of 5-HT1A regulation in medial prefrontal cortex GABA system of early postnatal-stressed rats
Shinichi Kimura, Yoshitaka Saito, Atsuko Ohashi, Sumitaka Inoue, Machiko Matsumoto, Hiroko Togashi, Masaru Minami, Hideya Saito, Hasan Parvez, Keiichi Shimamura

The selective serotonin re-uptake inhibitors / serotonin and noradrenaline re-uptake inhibitors in pregnancy: possible unfavorable effects on fetal and neurobehavioral development
Michal Dubovický

White Matter Lesions (WMLs): a probable risk factor for Ischemic Stroke in a subset of Pakistani Population
Ghazala Naveed, Ambreen Butt, Faraz A. Bokhari, Hasan S. Parvez

Somatization, but not depression, is characterized by disorders in the tryptophan catabolite (TRYCAT) pathway, indicating increased indoleamine 2,3-dioxygenase and lowered kynurenine aminotransferase activity
Michael Maes, Piotr Galecki, Robert Verkerk, Winfried Rief

Plasma dehydroepiandrosterone-sulphate is related to personality and stress response
Sónia do Vale, João Martin Martins, Maria João Fagundes, Isabel do Carmo

A Case of Sibutramine-induced hyperprolactinemia
Carolina Garcia Soares Leães, Júlia Fernanda Semmelmann Pereira-Lima, Miriam da Costa Oliveira